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胃癌の原因もいろいろ/飲み会したい

胃癌の原因と言ったら今の日本なら、ピロリ菌というのがまず一番に言われているのではないでしょうか?でも、胃癌のリスクっていっぱいあるのですよ。UpToDateにもいっぱいリスクが載っておりました。ある種の職業もリスクになるのですが、UpToDateでは、↓の数行だけの記載


Occupational exposures — There is some evidence that occupations in coal and tin mining, metal processing (particularly steel and iron), and rubber manufacturing industries lead to an increased risk of gastric cancer; however, the data are disparate


ちょっと不満ですので、↓の論文のご紹介


Airborne exposures and risk of gastric cancer: A prospective cohort study

https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.22566

Abstract

There is an unexplained male predominance among patients with gastric cancer, and many carcinogens are found in male-dominated dusty occupations. However, the relation between occupational exposures and risk of gastric cancer remains unclear. To investigate whether airborne occupational exposures might influence the risk of noncardia gastric cancer, we used a large, prospective cohort study of male Swedish construction workers. These workers were, during the period 1971-1993, regularly invited to health examinations by a nationwide occupational health service organization. Data on job titles and other variables were collected through self-administered questionnaires and forms completed by the health organization's staff. Industrial hygienists assessed 12 specific airborne occupational exposures for 200 job titles. Gastric cancer, death or emigration occurring during follow-up in 1971-2002 were identified by linkage to the Swedish registers of Cancer, Causes of Death and Total Population, respectively. Incidence rate ratios (IRR) and 95% confidence intervals (CI), adjusted for attained age, tobacco smoking, calendar period and body mass, were derived from Cox regression. Among 256,357 cohort members, contributing 5,378,012 person-years at risk, 948 noncardia gastric cancers were identified. Increased risk of this tumor was found among workers exposed to cement dust (IRR 1.5 [95% CI 1.1-2.1]), quartz dust (IRR 1.3 [95% CI 1.0-1.7]) and diesel exhaust (IRR 1.4 [95% CI 1.1-1.9]). Dose-response relations were observed for these exposures. No consistent positive associations were found regarding exposure to asbestos, asphalt fumes, concrete dust, epoxy resins, isocyanates, metal fumes, mineral fibers, organic solvents or wood dust. In conclusion, this study provides some support to the hypothesis that specific airborne exposures increase the risk of noncardia gastric cancer.

・医療機関で、除菌、除菌というのみでなく、職場環境もよくしてもらわないといけませんね。

以下あっという間に日記、かつ、あっという間に読める量

・本日7/13(土)はduty freeじゃなかったoff dutyでした。6時半頃起床です。1日論文の作成と事務作業をしておりました。夕方晴れたら草刈りしようと思っておりましたが、雨なので断念。これからお風呂入ります。で、アルコールを飲もうか否か悩んでいるところ。

・何か最近ストレスがたまっているので、数人の友達と飲み会がしたい気分であります。

 

 


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